Pulmonary embolism

Oxygen saturation as a prognostic marker in acute pulmonary embolism

. David Jiménez, Roger D Yusen, Juan Manuel Velasco, Raquel Morillo, Alfonso Muriel, Luis Jara-Palomares, Laurent Bertoletti, Luis Manuel Hernández-Blasco, Aída Gil-Díaz, Farès Moustafa, Ángeles Fidalgo, Parham Sadeghipour, Khanh Quoc Pham, Behnood Bikdeli, Manuel Monreal; RIETE Investigators. Oxygen saturation and mortality for acute pulmonary embolism: multinational retrospective cohort study. EClinicalMedicine. 2026 Apr 16:94:103889. doi: 10.1016/j.eclinm.2026.103889. eCollection 2026 Apr.

 

Improving long-term risk prediction after pulmonary embolism using machine learning

. Stephan Nopp, Clemens Spielvogel, Behnood Bikdeli, Ana Alberich-Conesa, Luis Hernández-Blasco, Mª Luisa Peris, Remedios Otero, David Jiménez, Manuel Monreal, Cihan Ay; RIETE Investigators. A machine learning approach to identify patients at risk for long-term consequences after pulmonary embolism. Sci Rep. 2025 Sep 24;15(1):32744. doi: 10.1038/s41598-025-14893-1.

 

The prognostic role of PaCO₂ in acute pulmonary embolism

. Diego Agustín Rodríguez-Chiaradía, José Gregorio González-García, Karys Khilzi, Benjamin Brenner, José Luis Fernández-Reyes, Judith Catella, Andris Skride, Antonio López-Ruiz, Hanh My Bui, Manuel Monreal; RIETE Investigators. The predictive value of PaCO2 in patients with pulmonary embolism: data from RIETE Registry. Arch Bronconeumol. 2026 Jan;62(1):53-56. doi: 10.1016/j.arbres.2025.07.008. Epub 2025 Jul 22.

 

Pulmonary embolism outcomes across different atherosclerotic disease profiles

. Silvia Cardi, Stefano Barco, Simon Wolf, Pablo Demelo-Rodríguez, Montserrat Pérez-Pinar, Andris Skride, Zoubida Tazi-Mezalek, Juan Bosco López-Sáez, Pablo Javier Marchena, Manuel Monreal; RIETE investigators. Characteristics and outcomes of acute pulmonary embolism among patients with polyvascular, single-vascular or no atherosclerotic disease: insights from RIETE. Clin Res Cardiol. 2026 Mar;115(3):472-483. doi: 10.1007/s00392-025-02706-4. Epub 2025 Jun 30.

 

A multimarker strategy to predict early outcomes in acute pulmonary embolism

. David Jiménez, Álvaro Dubois-Silva, Pablo Demelo-Rodríguez, Pedro Ruiz-Artacho, Juan José López-Núñez, Jorge Moisés, Alfonso Muriel, Alessandra Bura-Rivière, Isabelle Mahé, Giovanni Barillari, Behnood Bikdeli, Manuel Monreal; RIETE Investigators. Acute pulmonary embolism: a multimarker calculator to predict short-term outcomes. Eur Heart J. 2025 Dec 1;46(45):4921-4929. doi: 10.1093/eurheartj/ehaf228.

 

The obesity paradox revisited in acute pulmonary embolism

. Romain Chopard, Laurent Bertoletti, Marc Badoz, Nicolas Meneveau, Fiona Ecarnot, Luciano López Jiménez, Olga Madridano, José Antonio Díaz Peromingo, Meritxell López De la Fuente, Manuel Monreal, Gregory Piazza; RIETE Investigators. Lower early mortality and risk prediction improvement of obesity after acute pulmonary embolism: results from a multicenter cohort analysis with external validation. Res Pract Thromb Haemost. 2025 Feb 28;9(2):102718. doi: 10.1016/j.rpth.2025.102718. eCollection 2025 Feb.

 

Pulmonary embolism rule-out criteria in young adults: how safe is it?

. Thibaut Jossein, Lucia Mazzolai, Alicia Lorenzo Hernández, Sonia Otálora Valderrama, Marija Zdraveska, Agustina Rivas Guerrero, Antonio López Ruiz, Pierpaolo Di Micco, Manuel Monreal, Olivier Hugli; RIETE Investigators. Failure rate of the pulmonary embolism rule-out criteria rule for adults 35 years or younger: findings from the RIETE Registry. Acad Emerg Med. 2025 Apr;32(4):414-425. doi: 10.1111/acem.15046. Epub 2024 Nov 24.

 

Trends in mortality, recurrence and bleeding after pulmonary embolism

. Behnood Bikdeli, David Jiménez, Alfonso Muriel García, María Dolores Adarraga, Aitor Ballaz, Augustina Rivas-Guerrero, Paula Villares, Olga Gavín Sebastián, Diego Duran Barata, Maurizio Ciammaichella, Jose Meireles, Luis Ortega-Paz, My Hanh Bui, Manuel Monreal; RIETE Investigators. Trends in 90-day mortality, recurrent venous thrombosis, and bleeding in patients with pulmonary embolism. J Am Coll Cardiol. 2026 Apr 7;87(13):1539-1542. doi: 10.1016/j.jacc.2026.02.4874.

 

TAPSE/PASP ratio as a predictor of 30-day mortality in acute pulmonary embolism

. Mads Dam Lyhne, Behnood Bikdeli, David Jiménez, Christopher Kabrhel, David M. Dudzinski, Jorge Moisés, José Luis Lobo, Fernando Armestar, Leticia Guirado, Aitor Ballaz, Manuel Monreal; RIETE investigators. Right ventricular-pulmonary artery coupling for prognostication in acute pulmonary embolism. Eur Heart J Acute Cardiovasc Care. 2024 Dec 24;13(12):817-825. doi: 10.1093/ehjacc/zuae120.

 

Evaluating the failure rate of the PERC-35 rule in young adults with suspected PE

. Thibaut Jossein, Lucia Mazzolai, Alicia Lorenzo Hernández, Sonia Otálora Valderrama, Marija Zdraveska, Agustina Rivas Guerrero, Antonio López Ruiz, Pierpaolo di Micco, Manuel Monreal, Olivier Hugli; RIETE Investigators. Failure rate of the pulmonary embolism rule-out criteria rule for adults 35 years or younger: Findings from the RIETE Registry. Acad Emerg Med. 2024 Nov 24. doi: 10.1111/acem.15046. Online ahead of print.

 

Neutrophil-to-lymphocyte ratio as a prognostic marker?

. Fakiha Siddiqui, Alfonso Tafur, Mushtaq Hussain, Alberto García-Ortega, Amir Darki, Jawed Fareed, David Jiménez, Behnood Bikdeli, Francisco Galeano-Valle, José Luis Fernández-Reyes, Montserrat Pérez-Pinar, Manuel Monreal, RIETE Investigators. The prognostic value of blood cellular indices in pulmonary embolism. Am J Hematol. 2024 May 30. doi: 10.1002/ajh.27379. Online ahead of print.

 

Why to identify right ventricular dysfunction

. Mads Dam Lyhne , Behnood Bikdeli, David M. Dudzinski, Alfonso Muriel-García, Christopher Kabrhel, Teresa Sancho-Bueso, Esther Pérez-David, José Luis Lobo, Ángel Alonso-Gómez, David Jiménez, Manuel Monreal, RIETE Investigators. Validation of Echocardiographic Measurements in Patients with Pulmonary Embolism in the RIETE Registry. TH Open. 2024 Jan 8;8(1):e1-e8. doi: 10.1055/s-0043-1777765. eCollection 2024 Jan.

 

The SERIOUS-PE Study

. Behnood Bikdeli, Alfonso Muriel, Yun Wang, Gregory Piazza, Candrika D. Khairani, Rachel P. Rosovsky, Ghazaleh Mehdipoor, Michelle L. O’Donoghue, Olga Madridano, Juan Bosco López-Sáez, Meritxell Mellado, Ana María Díaz Brasero, Elvira Grandone, Primavera A. Spagnolo, Yuan Lu, Laurent Bertoletti, Luciano López-Jiménez, Manuel Jesús Núñez, Ángeles Blanco-Molina, Marie Gerhard-Herman, Samuel Z. Goldhaber, Shannon M. Bates, David Jiménez, Harlan M. Krumholz, Manuel Monreal, RIETE Investigators. Sex-Related Differences in Patient Characteristics, Risk Factors, and Symptomatology in Older Adults with Pulmonary Embolism: Findings from the SERIOUS-PE Study. Semin Thromb Hemost. 2023 Oct;49(7):725-735. doi: 10.1055/s-0043-1764231. Epub 2023 Mar 3.

 

How to identify patients at low risk of pulmonary embolism?

. David Jiménez , Behnood Bikdeli, Carmen Rodríguez, Alfonso Muriel, Aitor Ballaz, Silvia Soler, Sebastian Schellong, Aída Gil-Díaz, Andris Skride, Antoni Riera-Mestre, Manuel Monreal, RIETE Investigators. Identification of Low-risk Patients With Acute Symptomatic Pulmonary Embolism. Arch Bronconeumol. 2023 Sep;59(9):575-580. doi: 10.1016/j.arbres.2023.06.010. Epub 2023 Jul 4.

 

Safety of the pulmonary embolism rule-out criteria rule

. Perrine Truong, Lucia Mazzolai,Carme Font, Maurizio Ciammaichella, José González-Martínez, Antonella Tufano, Olga Gavín-Sebastián, Raphael Le Mao, Manuel Monreal, RIETE Investigators. Safety of the pulmonary embolism rule-out criteria rule: Findings from the Registro Informatizado de la Enfermedad TromboEmbolica venosa (RIETE) registry. Acad Emerg Med. 2023 Sep;30(9):935-945. doi: 10.1111/acem.14744. Epub 2023 May 31.

 

Statins and mortality in patients with pulmonary embolism

. Carmine Siniscalchi, Alfonso Muriel, José María Suriñach Caralt, Behnood Bikdeli, David Jiménez, José Luis Lobo, Cristina Amado, Aída Gil‐Díaz, Egidio Imbalzano, Manuel Monreal, RIETE Investigators. Statin use and 30‐day mortality in patients with acute symptomatic pulmonary embolism. J Thromb Haemost. 2022 Aug;20(8):1839-1851. doi: 10.1111/jth.15753. Epub 2022 May 22.

 

Syncope as a predictor of major bleeding events

. Ana Maestre, José Carlos Escribano, José Luis Lobo, Luis Jara-Palomares, David Jiménez, Behnood Bikdeli, Fernando Armestar, Alessandra Bura-Rivière, Alicia Lorenzo, Manuel Monreal, RIETE Investigators. Major bleeding in patients with pulmonary embolism presenting with syncope.Eur J Clin Invest. 2022 Jul;52(7):e13774. doi: 10.1111/eci.13774. Epub 2022 Mar 27.

 

Influence of acute kidney injury on the prognostic stratification

. Martin Murgier, Laurent Bertoletti, Behnood Bikdeli, David Jiménez, Javier Trujillo-Santos, Adel Merah, Cristina de Ancos, Ángeles Fidalgo, Jesús Aibar, Manuel Monreal, RIETE Investigators. Prognostic impact of acute kidney injury in patients with acute pulmonary embolism data from the RIETE registry. J Thromb Thrombolysis. 2022 Jul;54(1):58-66. doi: 10.1007/s11239-022-02633-5. Epub 2022 Jan 24.

 

Use of V/Q for the diagnosis of PE

. Pierre-Benoît Bonnefoy, Nathalie Prevot, Ghazaleh Mehdipoor, Alicia Sánchez, Jorge Lima, Llorenç Font, Aída Gil-Díaz, Pilar Llamas, Jesús Aibar, Behnood Bikdeli, Laurent Bertoletti, Manuel Monreal, and RIETE Investigators. Ventilation/perfusion (V/Q) scanning in contemporary patients with pulmonary embolism: utilization rates and predictors of use in a multinational study. J Thromb Thrombolysis. 2022 May;53(4):829-840. doi: 10.1007/s11239-021-02579-0. Epub 2021 Oct 5.

 

Patient characteristics according to the bleeding site

. Behnood Bikdeli, Farès Moustafa, José Antonio Nieto, Alfred I Lee, Nuria Ruíz-Giménez, Alicia Lorenzo, Sebastian Schellong, Silvia Soler, Salvador Ortiz, Mª del Valle Morales, Marijan Bosevski, Olga Gavín, Gregory Y H Lip, Manuel Monreal, RIETE Investigators. Clinical characteristics, time course, and outcomes of major bleeding according to bleeding site in patients with venous thromboembolism. Thromb Res. 2022 Mar;211:10-18. doi: 10.1016/j.thromres.2022.01.007. Epub 2022 Jan 14.

 

Japanese and pulmonary embolism

. Yugo Yamashita, Behnood Bikdeli, Manuel Monreal, Takeshi Morimoto, Takao Kato, Koh Ono, Cristina de Ancos, Juan J López-Núñez, Andrei Braester, Meritxell Mellado, Takeshi Kimura, COMMAND VTE Registry Investigators; RIETE Investigators. Difference between Japanese and White patients with acute pulmonary embolism. Thromb Res. 2021 Aug;204:52-56. doi: 10.1016/j.thromres.2021.06.008. Epub 2021 Jun 11.

 

Machine learning in pulmonary embolism

. Damián Mora, José A Nieto, Jorge Mateo, Behnood Bikdeli, Stefano Barco, Javier Trujillo-Santos, Silvia Soler, Llorenç Font, Marijan Bosevski, Manuel Monreal, RIETE Investigators. Machine learning to predict outcomes in patients with acute pulmonary embolism who prematurely discontinued anticoagulant therapy. Thromb Haemost. 2022 Apr;122(4):570-577. doi: 10.1055/a-1525-7220. Epub 2022 Jul 13.

 

Prediction of short-term mortality in elderly patients with acute PE

. Raquel Morillo, David Jiménez, Behnood Bikdeli, Carmen Rodríguez, Andrés Tenes, Yugo Yamashita, Takeshi Morimoto, Takeshi Kimura, Gemma Vidal, Nuria Ruiz-Giménez, Olivier Espitia, Manuel Monreal, RIETE investigators. Refinement of a modified simplified pulmonary embolism severity index for elderly patients with acute pulmonary embolism. Int J Cardiol. 2021 Jul 15;335:111-117. doi: 10.1016/j.ijcard.2021.02.039. Epub 2021 Feb 20.

 

Optimal therapy of patients with acute SPE?

. Carmen Fernández-Capitán, Ana Rodríguez Cobo, David Jiménez, Olga Madridano, Maurizio Ciammaichella, Esther Usandizaga, Remedios Otero, Pierpaolo Di Micco, Farès Moustafa, Manuel Monreal, RIETE Investigators. Symptomatic subsegmental versus more central pulmonary embolism: clinical outcomes during anticoagulationy. Res Pract Thromb Haemost. 2020 Nov 18;5(1):168-178. doi: 10.1002/rth2.12446. eCollection 2021 Jan.

 

Massive and non-massive pulmonary embolism

. Marc Blondon, David Jiménez, Helia Robert-Ebadi, Jorge Del Toro, Luciano López-Jímenez, Conxita Falgà, Andris Skride, Llorenç Font, Fernando Javier Vázquez, Henri Bounameaux , Manuel Monreal, RIETE investigators. Comparative clinical prognosis of massive and non-massive pulmonary embolism: A registry-based cohort study. J Thromb Haemost. 2021 Feb;19(2):408-416. doi: 10.1111/jth.15146. Epub 2020 Dec 19.

 

Imaging modalities for patients with acute pulmonary embolism

. Ghazaleh MehdipoorDavid JiménezLaurent BertolettiÁngeles FidalgoJuan Francisco Sánchez Muñoz-TorreroJosé Pedro González-MartínezÁngeles Blanco-MolinaMiguel Ángel AibarPierre-Benoît BonnefoyRamin KhorasaniMartin R PrinceBehnood BikdeliManuel MonrealRIETE Investigators. Patient-level, institutional, and temporal variations in use of imaging modalities to confirm pulmonary embolism. Circ Cardiovasc Imaging. 2020 May;13(5):e010651.doi: 10.1161/CIRCIMAGING.120.010651.

 

What is the BACS score?

. Luis Jara-PalomaresDavid JiménezBehnood BikdeliAlfonso MurielParth RaliYugo YamashitaTakeshi MorimotoTakeshi KimuraRaphael Le MaoAntoni Riera-MestreAna MaestreFarès MoustafaManuel MonrealRIETE Investigators. Derivation and validation of a clinical prediction rule for thrombolysis-associated major bleeding in patients with acute pulmonary embolism: the BACS score. Eur Respir J. 2020 Jul 23;2002336. doi: 10.1183/13993003.02336-2020.

 

Optimal cutoff for systolic blood pressure level to define high-risk pulmonary embolism

. Andrés QuezadaDavid JiménezBehnood BikdeliLisa MooresMateo Porres-AguilarMario AramberriJorge LimaAitor BallazRoger D YusenManuel MonrealRIETE investigators. Systolic blood pressure and mortality in acute symptomatic pulmonary embolism. Int j Cardiol. 2020 Mar 1;302:157-163. doi: 10.1016/j.ijcard.2019.11.102.

 

Is diabetes a predictor for death in pulmonary embolism?

. Javier de Miguel-DíezAna López-de-AndrésIsabel Jiménez-TrujilloValentín Hernández-BarreraRodrigo Jiménez-GarcíaAlicia LorenzoJosé M PedrajasAdriana VisonàPatricia López-MiguelManuel MonrealRIETE Investigators. Mortality after pulmonary embolism in patients with diabetes. Findings from the RIETE Registry. Eur. J Intern Med. 2019 Jan;59:46-52. doi: 10.1016/j.ejim.2018.08.001.

 

SBP levels on admission and mortality in patients with acute symptomatic PE

. Andrés QuezadaDavid JiménezBehnood BikdeliLisa MooresMateo Porres-AguilarMario AramberriJorge LimaAitor BallazRoger D YusenManuel MonrealRIETE Investigators. Systolic blood pressure and mortality in acute symptomatic pulmonary embolism. Int. J Cardiol. Mar 1;302:157-163. doi: 10.1016/j.ijcard.2019.11.102.

 

How is the therapy for acute pulmonary embolism in different countries?

. Daniela MastroiacovoFrancesco DentaliPierpaolo di MiccoAna MaestreDavid JiménezSilvia SolerJoan Carles SahuquilloPeter VerhammeÁngeles FidalgoJuan Bosco López-SáezAndris SkrideManuel MonrealRIETE InvestigatorsCoordinator of the RIETE Registry: Manuel Monreal (Spain). RIETE Steering Committee Members:Members of the RIETE Group are as follows. Spain. Rate and duration of hospitalisation for acute pulmonary embolism in the real-world clinical practice of different countries: analysis from the RIETE Registry. Eur. Respir J. 2019 Feb 21;53(2):1801677. doi: 10.1183/13993003.01677-2018.

 

Incidence and time-course of fatal PE and fatal bleeding in real-life clinical practice

. Manuel Monreal. Fatal pulmonary embolism or bleeding in patients with venous thromboembolism: implications of real-life data. Thromb. Res. 2019 Sep;181 Suppl 1:S6-S9. doi: 10.1016/S0049-3848(19)30358-5.

 

Management strategies for acute pulmonary embolism

. David JiménezBehnood BikdeliAndrés QuezadaAlfonso MurielJosé Luis LoboJavier de Miguel-DíezLuis Jara-PalomaresPedro Ruiz-ArtachoRoger D YusenManuel MonrealRIETE Investigators. Hospital volume and outcomes for acute pulmonary embolism: multinational population based cohort study. BMJ. 2019 Jul 29;366:l4416. doi: 10.1136/bmj.l4416.

 

Prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

. Luis Jara-PalomaresMaria AlfonsoAna MaestreDavid JiménezFernando García-BragadoCarme FontRaquel López ReyesLuis Hernández BlascoGemma VidalRemedios OteroManuel MonrealRIETE Investigators. Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years. Sci Rep. 2019 Dec 27;9(1):20064. doi: 10.1038/s41598-019-55213-8.

 

A review of published studies on patients with unstable PE

Jiménez D, Bikdeli B, Barrios D, Quezada A, Del Toro J, Vidal G, Mahé I, Quere I, Loring M, Yusen RD, Monreal M; RIETE investigators. Epidemiology, patterns of care and mortality for patients with hemodynamically unstable acute symptomatic pulmonary embolism. Int J Cardiol. 2018 Oct 15;269:327-333. doi: 10.1016/j.ijcard.2018.07.059. Epub 2018 Jul 17.

 

Does diabetes impact on outcomes in patients with PE?

. De Miguel-Díez J, López-de-Andrés A, Jiménez-Trujillo I, Hernández-Barrera V, Jiménez-García R, Lorenzo A, Pedrajas JM, Visonà A, López-Miguel P, Monreal M; RIETE Investigators. Mortality after pulmonary embolism in patients with diabetes. Findings from the RIETE registry. Eur J Intern Med. 2018 Aug 9. pii: S0953-6205(18)30319-4. doi: 10.1016/j.ejim.2018.08.001.

 

Clinical consequences of not adhering to guidelines recommendations when treating acute PE

Jiménez D, Bikdeli B, Barrios D, Morillo R, Nieto R, Guerassimova I, Muriel A, Jara-Palomares L, Moores L, Tapson V, Yusen RD, Monreal M; RIETE investigators. Management appropriateness and outcomes of patients with acute pulmonary embolism. Eur Respir J. 2018 May 10;51(5). pii: 1800445. doi: 10.1183/13993003.00445-2018

 

Predicting CTEPH in PE patients

. Otero R, Bertoletti L, Muriel A, Siniscalchi C, Jimenez C, Luis Lobo J, Kigitovica D, Quintavalla R, Rocci A, Jara-Palomares L, Monreal YM; RIETE Investigators. Role of a clinical prediction score in a CTEPH rule-out strategy. Eur Respir J. 2018 Mar 1. pii: 1702576. doi: 10.1183/13993003.02576-2017.

 

Clinical prognosis of nonmassive central and noncentral pulmonary embolism

. Gouin B, Blondon M, Jiménez D, Fernández-Capitán C, Bounameaux H, Soler S, Duce R, Sahuquillo JC, Ruiz-Giménez N, Monreal M; RIETE investigators. Clinical Prognosis of Nonmassive Central and Noncentral Pulmonary Embolism: A Registry-Based Cohort Study. Chest. 2017 Apr;151(4):829-837. doi: 10.1016/j.chest.2016.10.056. Epub 2016 Nov 19.

 

Heart thrombi in pulmonary embolism

. Barrios D, Rosa-Salazar V, Jiménez D, Morillo R, Muriel A, Del Toro J, López-Jiménez L, Farge-Bancel D, Yusen R, Monreal M; RIETE investigators. Right heart thrombi in pulmonary embolism. Eur Respir J. 2016 Nov;48(5):1377-1385. doi: 10.1183/13993003.01044-2016. Epub 2016 Oct 6.

 

Trends in the management of acute pulmonary embolism

. Jiménez D, de Miguel-Díez J, Guijarro R, Trujillo-Santos J, Otero R, Barba R, Muriel A, Meyer G, Yusen RD, Monreal M; RIETE Investigators. Trends in the Management and Outcomes of Acute Pulmonary Embolism: Analysis From the RIETE Registry. J Am Coll Cardiol. 2016 Jan 19;67(2):162-170. doi: 10.1016/j.jacc.2015.10.060.

 

Identification of patients with low risk PE

. Maestre A, Trujillo-Santos J, Riera-Mestre A, Jiménez D, Di Micco P, Bascuñana J, Vela JR, Peris L, Malfante PC, Monreal M and the RIETE Investigators. Identification of low-risk patients with acute symptomatic pulmonary embolism for outpatient therapy. Ann Am Thorac Soc 2015 Aug; 12(8): 1122-9.

 

Prognostic value of the echocardiogram

. Lobo JL, Holley A, Tapson V, Moores L, Oribe M, Barrón M, Otero R, Nauffal D, Valle R, Monreal M, Yusen RD, Jiménez D; PROTECT and RIETE investigators. Prognostic significance of tricuspid annular displacement in normotensive patients with acute symptomatic pulmonary embolism. J Thromb Haemost 2014 Jul; 12 (7): 1020-7.

 

D-dimer and 90-day outcome

. Maestre A, Trujillo-Santos J, Visoná A, Lobo JL, Grau E, Malý R, Duce R, Monreal M and the RIETE Investigators. D-dimer levels and 90-day outcome in patients with acute pulmonary embolism with or without cancer. Thromb Res 2014 Mar; 133(3): 384-9.

 

PE in COPD patients

. Bertoletti L, Quenet S, Laporte S, Sahuquillo JC, Conget F, Pedrajas JM, Martín M, Casado I, Riera-Mestre A, Monreal M and the RIETE investigators. Pulmonary embolism and 3-month outcomes in 4036 patients with venous thromboembolism and chronic obstructive pulmonary disease: data from the RIETE registry. Respir Res 2013 Jul; 14(1): 75.

 

Factors associated with pulmonary artery hypertension

. Otero R, Elías T, Jara L, Trujillo-Santos J, Bertoletti L, Nauffal D, Ruiz-Ruiz J, Blanco-Molina A, Monreal M and the RIETE investigators. Factors associated with elevated pulmonary arterial pressure levels on the echocardiographic assessment in patients with prior pulmonary embolism. Thromb Res 2013 May; 131(5): e191-e195.

 

Prior immobility or surgery in patients with PE

. Nauffal D, Ballester M, Reyes RL, Jiménez D, Otero R, Quintavalla R, Monreal M; and the RIETE investigators. Influence of recent immobilization and recent surgery on mortality in patients with pulmonary embolism. J Thromb Haemost 2012 Sep; 10(9): 1752-60.

 

Thrombolysis in PE

. Riera-Mestre A, Jiménez D, Muriel A, Lobo JL, Moores L, Yusen RD, Casado I, Nauffal D, Oribe M, Monreal M, for the RIETE investigators. Thrombolytic therapy and outcome of patients with an acute symptomatic pulmonary embolism. J. Thromb Haemost 2012 May; 10(5): 751-9.

 

Simplified PESI score

. Jiménez D, Aujesky D, Moores L, Gómez V, Lobo JL, Uresandi F, Otero R, Monreal M, Muriel A, Yusen R for the RIETE Investigators. Simplification of pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med 2010 Aug; 170(15): 1383-9.

 

Concomitant DVT in patients with PE

. Jiménez D, Aujesky D, Díaz G, Monreal M, Otero R, Martí D, Marín E, Aracil E, Sueiro A, Yusen RD and the RIETE Investigators. Prognostic significance of deep vein thrombosis in patients presenting with acute symtomatic pulmonary embolism. Am J Respir Crit Care Med 2010 May; 181(9): 983-91.

 

D-dimer levels and 15 days outcome

. Lobo JL, Zorrilla V, Aizpuru F, Grau E, Jiménez D, Palareti G, Monreal M and the RIETE investigators. D-dimer levels and 15-day outcome in acute pulmonary embolism. Findings from the RIETE Registry. J Thromb Haemost 2009 Nov; 7(11): 1795-801.

 

Chest x-ray and EKG in PE

. Nauffal D, Domènech R, León M, Bugés J, Martín-Villasclaras JJ y los investigadores del Registro RIETE. Papel de las alteraciones radiográficas y del electrocardiograma en la predicción de mortalidad y recidivas en pacientes con embolia pulmón. Med Clin 2009 Mar 28; 132(11): 420-2.

 

Predictors of fatal PE

. Laporte S, Mismetti P, Décousus H, Uresandi F, Otero R, Lobo JL, Monreal M and the RIETE investigators. Clinical predictors for fatal pulmonary embolism in 15,520 patients with venous thromboembolism. Findings from the Registro Informatizado de la Enfermedad Tromboembólica venosa (RIETE) Registry. Circulation 2008 Apr; 117(13): 1711-6.

 

PE unstable hemodynamically

. Otero R, Trujillo-Santos J, Cayuela A, Rodríguez C, Barrón M, Martín JJ, Monreal M for the RIETE Investigators. Haemodynamically unstable pulmonary embolism in the RIETE Registry: systolic blood pressure or shock index? Eur Respir J 2007 Dec; 30(6): 1111-6.

 

D-dimer levels and ouctcome

. Grau E, Tenías JM, Soto MJ, Gutiérrez MR, Lecumberri R, Pérez JL, Tiberio G for the RIETE Investigators. D-dimer levels correlate with mortality in patients with acute pulmonary embolism: Findings from the RIETE Registry. Crit Care Med 2007 Aug; 35 (8): 1937-41.

 

Clinical syndromes of PE

. Lobo JL, Zorrilla V, Aizpuru F, Uresandi F, García-Bragado F, Conget F, Monreal M for the RIETE Investigators. Clinical syndromes and clinical outcome in patients with pulmonary embolism: findings from the RIETE Registry. Chest 2006 Dec; 130(6): 1817-22.

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The RIETE Registry is the world’s largest database on patients with venous thromboembolism (VTE).

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June 2026

 

 

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