Pulmonary embolism

Syncope as a predictor of major bleeding events

. Ana Maestre, José Carlos Escribano, José Luis Lobo, Luis Jara-Palomares, David Jiménez, Behnood Bikdeli, Fernando Armestar, Alessandra Bura-Rivière, Alicia Lorenzo, Manuel Monreal, RIETE Investigators. Major bleeding in patients with pulmonary embolism presenting with syncope.Eur J Clin Invest. 2022 Jul;52(7):e13774. doi: 10.1111/eci.13774. Epub 2022 Mar 27.

 

Influence of acute kidney injury on the prognostic stratification

. Martin Murgier, Laurent Bertoletti, Behnood Bikdeli, David Jiménez, Javier Trujillo-Santos, Adel Merah, Cristina de Ancos, Ángeles Fidalgo, Jesús Aibar, Manuel Monreal, RIETE Investigators. Prognostic impact of acute kidney injury in patients with acute pulmonary embolism data from the RIETE registry. J Thromb Thrombolysis. 2022 Jul;54(1):58-66. doi: 10.1007/s11239-022-02633-5. Epub 2022 Jan 24.

 

Use of V/Q for the diagnosis of PE

. Pierre-Benoît Bonnefoy, Nathalie Prevot, Ghazaleh Mehdipoor, Alicia Sánchez, Jorge Lima, Llorenç Font, Aída Gil-Díaz, Pilar Llamas, Jesús Aibar, Behnood Bikdeli, Laurent Bertoletti, Manuel Monreal, and RIETE Investigators. Ventilation/perfusion (V/Q) scanning in contemporary patients with pulmonary embolism: utilization rates and predictors of use in a multinational study. J Thromb Thrombolysis. 2022 May;53(4):829-840. doi: 10.1007/s11239-021-02579-0. Epub 2021 Oct 5.

 

Japanese and pulmonary embolism

. Yugo Yamashita, Behnood Bikdeli, Manuel Monreal, Takeshi Morimoto, Takao Kato, Koh Ono, Cristina de Ancos, Juan J López-Núñez, Andrei Braester, Meritxell Mellado, Takeshi Kimura, COMMAND VTE Registry Investigators; RIETE Investigators. Difference between Japanese and White patients with acute pulmonary embolism. Thromb Res. 2021 Aug;204:52-56. doi: 10.1016/j.thromres.2021.06.008. Epub 2021 Jun 11.

 

Machine learning in pulmonary embolism

. Damián Mora, José A Nieto, Jorge Mateo, Behnood Bikdeli, Stefano Barco, Javier Trujillo-Santos, Silvia Soler, Llorenç Font, Marijan Bosevski, Manuel Monreal, RIETE Investigators. Machine learning to predict outcomes in patients with acute pulmonary embolism who prematurely discontinued anticoagulant therapy. Thromb Haemost. 2022 Apr;122(4):570-577. doi: 10.1055/a-1525-7220. Epub 2022 Jul 13.

 

Prediction of short-term mortality in elderly patients with acute PE

. Raquel Morillo, David Jiménez, Behnood Bikdeli, Carmen Rodríguez, Andrés Tenes, Yugo Yamashita, Takeshi Morimoto, Takeshi Kimura, Gemma Vidal, Nuria Ruiz-Giménez, Olivier Espitia, Manuel Monreal, RIETE investigators. Refinement of a modified simplified pulmonary embolism severity index for elderly patients with acute pulmonary embolism. Int J Cardiol. 2021 Jul 15;335:111-117. doi: 10.1016/j.ijcard.2021.02.039. Epub 2021 Feb 20.

 

Optimal therapy of patients with acute SPE?

. Carmen Fernández-Capitán, Ana Rodríguez Cobo, David Jiménez, Olga Madridano, Maurizio Ciammaichella, Esther Usandizaga, Remedios Otero, Pierpaolo Di Micco, Farès Moustafa, Manuel Monreal, RIETE Investigators. Symptomatic subsegmental versus more central pulmonary embolism: clinical outcomes during anticoagulationy. Res Pract Thromb Haemost. 2020 Nov 18;5(1):168-178. doi: 10.1002/rth2.12446. eCollection 2021 Jan.

 

Massive and non-massive pulmonary embolism

. Marc Blondon, David Jiménez, Helia Robert-Ebadi, Jorge Del Toro, Luciano López-Jímenez, Conxita Falgà, Andris Skride, Llorenç Font, Fernando Javier Vázquez, Henri Bounameaux , Manuel Monreal, RIETE investigators. Comparative clinical prognosis of massive and non-massive pulmonary embolism: A registry-based cohort study. J Thromb Haemost. 2021 Feb;19(2):408-416. doi: 10.1111/jth.15146. Epub 2020 Dec 19.

 

Imaging modalities for patients with acute pulmonary embolism

. Ghazaleh Mehdipoor, David Jiménez, Laurent Bertoletti, Ángeles Fidalgo, Juan Francisco Sánchez Muñoz-Torrero, José Pedro González-Martínez, Ángeles Blanco-Molina, Miguel Ángel Aibar, Pierre-Benoît Bonnefoy, Ramin Khorasani, Martin R Prince, Behnood Bikdeli, Manuel Monreal, RIETE Investigators. Patient-level, institutional, and temporal variations in use of imaging modalities to confirm pulmonary embolism. Circ Cardiovasc Imaging. 2020 May;13(5):e010651.doi: 10.1161/CIRCIMAGING.120.010651.

 

What is the BACS score?

. Luis Jara-Palomares, David Jiménez, Behnood Bikdeli, Alfonso Muriel, Parth Rali, Yugo Yamashita, Takeshi Morimoto, Takeshi Kimura, Raphael Le Mao, Antoni Riera-Mestre, Ana Maestre, Farès Moustafa, Manuel Monreal, RIETE Investigators. Derivation and validation of a clinical prediction rule for thrombolysis-associated major bleeding in patients with acute pulmonary embolism: the BACS score. Eur Respir J. 2020 Jul 23;2002336. doi: 10.1183/13993003.02336-2020.

 

Optimal cutoff for systolic blood pressure level to define high-risk pulmonary embolism

. Andrés Quezada, David Jiménez, Behnood Bikdeli, Lisa Moores, Mateo Porres-Aguilar, Mario Aramberri, Jorge Lima, Aitor Ballaz, Roger D Yusen, Manuel Monreal, RIETE investigators. Systolic blood pressure and mortality in acute symptomatic pulmonary embolism. Int j Cardiol. 2020 Mar 1;302:157-163. doi: 10.1016/j.ijcard.2019.11.102.

 

Is diabetes a predictor for death in pulmonary embolism?

. Javier de Miguel-Díez, Ana López-de-Andrés, Isabel Jiménez-Trujillo, Valentín Hernández-Barrera, Rodrigo Jiménez-García, Alicia Lorenzo, José M Pedrajas, Adriana Visonà, Patricia López-Miguel, Manuel Monreal, RIETE Investigators. Mortality after pulmonary embolism in patients with diabetes. Findings from the RIETE Registry. Eur. J Intern Med. 2019 Jan;59:46-52. doi: 10.1016/j.ejim.2018.08.001.

 

SBP levels on admission and mortality in patients with acute symptomatic PE

. Andrés Quezada, David Jiménez, Behnood Bikdeli, Lisa Moores, Mateo Porres-Aguilar, Mario Aramberri, Jorge Lima, Aitor Ballaz, Roger D Yusen, Manuel Monreal, RIETE Investigators. Systolic blood pressure and mortality in acute symptomatic pulmonary embolism. Int. J Cardiol. Mar 1;302:157-163. doi: 10.1016/j.ijcard.2019.11.102.

 

How is the therapy for acute pulmonary embolism in different countries?

. Daniela Mastroiacovo, Francesco Dentali, Pierpaolo di Micco, Ana Maestre, David Jiménez, Silvia Soler, Joan Carles Sahuquillo, Peter Verhamme, Ángeles Fidalgo, Juan Bosco López-Sáez, Andris Skride, Manuel Monreal, RIETE Investigators; Coordinator of the RIETE Registry: Manuel Monreal (Spain). RIETE Steering Committee Members:; Members of the RIETE Group are as follows. Spain. Rate and duration of hospitalisation for acute pulmonary embolism in the real-world clinical practice of different countries: analysis from the RIETE Registry. Eur. Respir J. 2019 Feb 21;53(2):1801677. doi: 10.1183/13993003.01677-2018.

 

Incidence and time-course of fatal PE and fatal bleeding in real-life clinical practice

. Manuel Monreal. Fatal pulmonary embolism or bleeding in patients with venous thromboembolism: implications of real-life data. Thromb. Res. 2019 Sep;181 Suppl 1:S6-S9. doi: 10.1016/S0049-3848(19)30358-5.

 

Management strategies for acute pulmonary embolism

. David Jiménez, Behnood Bikdeli, Andrés Quezada, Alfonso Muriel, José Luis Lobo, Javier de Miguel-Díez, Luis Jara-Palomares, Pedro Ruiz-Artacho, Roger D Yusen, Manuel Monreal, RIETE Investigators. Hospital volume and outcomes for acute pulmonary embolism: multinational population based cohort study. BMJ. 2019 Jul 29;366:l4416. doi: 10.1136/bmj.l4416.

 

Prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

. Luis Jara-Palomares, Maria Alfonso, Ana Maestre, David Jiménez, Fernando García-Bragado, Carme Font, Raquel López Reyes, Luis Hernández Blasco, Gemma Vidal, Remedios Otero, Manuel Monreal, RIETE Investigators. Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years. Sci Rep. 2019 Dec 27;9(1):20064. doi: 10.1038/s41598-019-55213-8.

 

A review of published studies on patients with unstable PE

. Jiménez D, Bikdeli B, Barrios D, Quezada A, Del Toro J, Vidal G, Mahé I, Quere I, Loring M, Yusen RD, Monreal M; RIETE investigators. Epidemiology, patterns of care and mortality for patients with hemodynamically unstable acute symptomatic pulmonary embolism. Int J Cardiol. 2018 Oct 15;269:327-333. doi: 10.1016/j.ijcard.2018.07.059. Epub 2018 Jul 17.

 

Does diabetes impact on outcomes in patients with PE?

. De Miguel-Díez J, López-de-Andrés A, Jiménez-Trujillo I, Hernández-Barrera V, Jiménez-García R, Lorenzo A, Pedrajas JM, Visonà A, López-Miguel P, Monreal M; RIETE Investigators. Mortality after pulmonary embolism in patients with diabetes. Findings from the RIETE registry. Eur J Intern Med. 2018 Aug 9. pii: S0953-6205(18)30319-4. doi: 10.1016/j.ejim.2018.08.001.

 

Clinical consequences of not adhering to guidelines recommendations when treating acute PE

. Jiménez D, Bikdeli B, Barrios D, Morillo R, Nieto R, Guerassimova I, Muriel A, Jara-Palomares L, Moores L, Tapson V, Yusen RD, Monreal M; RIETE investigators. Management appropriateness and outcomes of patients with acute pulmonary embolism. Eur Respir J. 2018 May 10;51(5). pii: 1800445. doi: 10.1183/13993003.00445-2018

 

Predicting CTEPH in PE patients

. Otero R, Bertoletti L, Muriel A, Siniscalchi C, Jimenez C, Luis Lobo J, Kigitovica D, Quintavalla R, Rocci A, Jara-Palomares L, Monreal YM; RIETE Investigators. Role of a clinical prediction score in a CTEPH rule-out strategy. Eur Respir J. 2018 Mar 1. pii: 1702576. doi: 10.1183/13993003.02576-2017.

 

Clinical prognosis of nonmassive central and noncentral pulmonary embolism

. Gouin B, Blondon M, Jiménez D, Fernández-Capitán C, Bounameaux H, Soler S, Duce R, Sahuquillo JC, Ruiz-Giménez N, Monreal M; RIETE investigators. Clinical Prognosis of Nonmassive Central and Noncentral Pulmonary Embolism: A Registry-Based Cohort Study. Chest. 2017 Apr;151(4):829-837. doi: 10.1016/j.chest.2016.10.056. Epub 2016 Nov 19.

 

Heart thrombi in pulmonary embolism

. Barrios D, Rosa-Salazar V, Jiménez D, Morillo R, Muriel A, Del Toro J, López-Jiménez L, Farge-Bancel D, Yusen R, Monreal M; RIETE investigators. Right heart thrombi in pulmonary embolism. Eur Respir J. 2016 Nov;48(5):1377-1385. doi: 10.1183/13993003.01044-2016. Epub 2016 Oct 6.

 

Trends in the management of acute pulmonary embolism

. Jiménez D, de Miguel-Díez J, Guijarro R, Trujillo-Santos J, Otero R, Barba R, Muriel A, Meyer G, Yusen RD, Monreal M; RIETE Investigators. Trends in the Management and Outcomes of Acute Pulmonary Embolism: Analysis From the RIETE Registry. J Am Coll Cardiol. 2016 Jan 19;67(2):162-170. doi: 10.1016/j.jacc.2015.10.060.

 

Identification of patients with low risk PE

. Maestre A, Trujillo-Santos J, Riera-Mestre A, Jiménez D, Di Micco P, Bascuñana J, Vela JR, Peris L, Malfante PC, Monreal M and the RIETE Investigators. Identification of low-risk patients with acute symptomatic pulmonary embolism for outpatient therapy. Ann Am Thorac Soc 2015 Aug; 12(8): 1122-9.

 

Prognostic value of the echocardiogram

. Lobo JL, Holley A, Tapson V, Moores L, Oribe M, Barrón M, Otero R, Nauffal D, Valle R, Monreal M, Yusen RD, Jiménez D; PROTECT and RIETE investigators. Prognostic significance of tricuspid annular displacement in normotensive patients with acute symptomatic pulmonary embolism. J Thromb Haemost 2014 Jul; 12 (7): 1020-7.

 

D-dimer and 90-day outcome

. Maestre A, Trujillo-Santos J, Visoná A, Lobo JL, Grau E, Malý R, Duce R, Monreal M and the RIETE Investigators. D-dimer levels and 90-day outcome in patients with acute pulmonary embolism with or without cancer. Thromb Res 2014 Mar; 133(3): 384-9.

 

PE in COPD patients

. Bertoletti L, Quenet S, Laporte S, Sahuquillo JC, Conget F, Pedrajas JM, Martín M, Casado I, Riera-Mestre A, Monreal M and the RIETE investigators. Pulmonary embolism and 3-month outcomes in 4036 patients with venous thromboembolism and chronic obstructive pulmonary disease: data from the RIETE registry. Respir Res 2013 Jul; 14(1): 75.

 

Factors associated with pulmonary artery hypertension

. Otero R, Elías T, Jara L, Trujillo-Santos J, Bertoletti L, Nauffal D, Ruiz-Ruiz J, Blanco-Molina A, Monreal M and the RIETE investigators. Factors associated with elevated pulmonary arterial pressure levels on the echocardiographic assessment in patients with prior pulmonary embolism. Thromb Res 2013 May; 131(5): e191-e195.

 

Prior immobility or surgery in patients with PE

. Nauffal D, Ballester M, Reyes RL, Jiménez D, Otero R, Quintavalla R, Monreal M; and the RIETE investigators. Influence of recent immobilization and recent surgery on mortality in patients with pulmonary embolism. J Thromb Haemost 2012 Sep; 10(9): 1752-60.

 

Thrombolysis in PE

. Riera-Mestre A, Jiménez D, Muriel A, Lobo JL, Moores L, Yusen RD, Casado I, Nauffal D, Oribe M, Monreal M, for the RIETE investigators. Thrombolytic therapy and outcome of patients with an acute symptomatic pulmonary embolism. J. Thromb Haemost 2012 May; 10(5): 751-9.

 

Simplified PESI score

. Jiménez D, Aujesky D, Moores L, Gómez V, Lobo JL, Uresandi F, Otero R, Monreal M, Muriel A, Yusen R for the RIETE Investigators. Simplification of pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism. Arch Intern Med 2010 Aug; 170(15): 1383-9.

 

Concomitant DVT in patients with PE

. Jiménez D, Aujesky D, Díaz G, Monreal M, Otero R, Martí D, Marín E, Aracil E, Sueiro A, Yusen RD and the RIETE Investigators. Prognostic significance of deep vein thrombosis in patients presenting with acute symtomatic pulmonary embolism. Am J Respir Crit Care Med 2010 May; 181(9): 983-91.

 

D-dimer levels and 15 days outcome

. Lobo JL, Zorrilla V, Aizpuru F, Grau E, Jiménez D, Palareti G, Monreal M and the RIETE investigators. D-dimer levels and 15-day outcome in acute pulmonary embolism. Findings from the RIETE Registry. J Thromb Haemost 2009 Nov; 7(11): 1795-801.

 

Chest x-ray and EKG in PE

. Nauffal D, Domènech R, León M, Bugés J, Martín-Villasclaras JJ y los investigadores del Registro RIETE. Papel de las alteraciones radiográficas y del electrocardiograma en la predicción de mortalidad y recidivas en pacientes con embolia pulmón. Med Clin 2009 Mar 28; 132(11): 420-2.

 

Predictors of fatal PE

. Laporte S, Mismetti P, Décousus H, Uresandi F, Otero R, Lobo JL, Monreal M and the RIETE investigators. Clinical predictors for fatal pulmonary embolism in 15,520 patients with venous thromboembolism. Findings from the Registro Informatizado de la Enfermedad Tromboembólica venosa (RIETE) Registry. Circulation 2008 Apr; 117(13): 1711-6.

 

PE unstable hemodynamically

. Otero R, Trujillo-Santos J, Cayuela A, Rodríguez C, Barrón M, Martín JJ, Monreal M for the RIETE Investigators. Haemodynamically unstable pulmonary embolism in the RIETE Registry: systolic blood pressure or shock index? Eur Respir J 2007 Dec; 30(6): 1111-6.

 

D-dimer levels and ouctcome

. Grau E, Tenías JM, Soto MJ, Gutiérrez MR, Lecumberri R, Pérez JL, Tiberio G for the RIETE Investigators. D-dimer levels correlate with mortality in patients with acute pulmonary embolism: Findings from the RIETE Registry. Crit Care Med 2007 Aug; 35 (8): 1937-41.

 

Clinical syndromes of PE

. Lobo JL, Zorrilla V, Aizpuru F, Uresandi F, García-Bragado F, Conget F, Monreal M for the RIETE Investigators. Clinical syndromes and clinical outcome in patients with pulmonary embolism: findings from the RIETE Registry. Chest 2006 Dec; 130(6): 1817-22.