VTE in special situations

Venous thromboembolism in ankylosing spondylitis: how does it compare?

. Romain Chopard, Gregory Piazza, Laurent Bertoletti, Nicolas Meneveau, Leticia Guirado, José Antonio Porras, Francisco Rivera-Cívico, José Felipe Varona Arche, Manuel Monreal, Clément Prati; RIETE Investigators. Clinical outcomes of venous thromboembolism in patients with ankylosing spondylitis vs. other immune-mediated inflammatory diseases: insights from the RIETE Registry. Thromb Haemost. 2025 Nov 12. doi: 10.1055/a-2722-7327. Online ahead of print.

Venous thromboembolism in patients aged 90 years and older

. Ludovic Lafaie, Géraldine Poenou, Olivier Hanon, Sonia Otálora, Luciano López Jiménez, Aitor Ballaz, Silvia Soler, Manuel Jesús Núñez Fernández, Laurent Bertoletti, Manuel Monreal; RIETE investigators. Venous thromboembolism in patients aged ≥90 years: trends in clinical features, treatment, and outcomes—RIETE registry. J Am Geriatr Soc. 2025 Apr;73(4):1219-1226. doi: 10.1111/jgs.19306. Epub 2024 Dec 3.

Venous thromboembolism after hospital discharge: changing patterns over tim

. Benjamin Brenner, Inna Tzoran, Behnood Bikdeli, Reina Valle, Géraldine Poenou, Raimundo Tirado-Miranda, María L Pesce, Javier Pagán-Escribano, Matteo Giorgi-Pierfranceschi, Manuel Monreal; RIETE Investigators. Venous thromboembolism after hospital discharge: temporal trends in baseline characteristics, prevention, treatment, and 90-day outcomes. Semin Thromb Hemost
. 2025 Apr;51(3):301-311. doi: 10.1055/s-0044-1791817. Epub 2024 Oct 17.

Association between FIB-4 levels and rates of major bleeding

. Diego Martínez-Urbistondo, Rocío G de la Garza, Paula Villares-Fernández, Carme Font, Sebastian Schellong, Juan José López-Núñez, Aída Gil-Díaz, María del Carmen Díaz-Pedroche, Jana Hirmerova, Manuel Monreal, RIETE Investigators. Liver status and outcomes in patients without previous known liver disease receiving anticoagulant therapy for venous thromboembolism. Semin Thromb Hemost. 2025 Apr;51(3):301-311. doi: 10.1055/s-0044-1791817. Epub 2024 Oct 17.

Imaging modalities for confirming pulmonary embolism of pregnancy

. Ghazaleh Mehdipoor, David Jiménez, Laurent Bertoletti, Jorge Del Toro, Carmen Fernández-Capitán, Alessandra Bura-Riviere, Cristina Amado, Beatriz Valero, Ángeles Blanco-Molina, Remedios Otero, Egidio Imbalzano, Ramin Khorasani, Martin R. Prince, Behnood Bikdeli, Manuel Monreal and the RIETE Investigators. Imaging modalities for confirming pulmonary embolism during pregnancy: results from a multicenter international study. Eur Radiol. 2022 Feb;32(2):1238-1246. doi: 10.1007/s00330-021-08161-9. Epub 2021 Jul 30.

Atrial fibrillation and pulmonary embolism

. Behnood Bikdeli, David Jiménez, Jorge Del Toro, Gregory Piazza, Agustina Rivas, José Luis Fernández-Reyes, Ángel Sampériz, Remedios Otero, José María Suriñach, Carmine Siniscalchi, Javier Miguel Martín-Guerra, Joaquín Castro, Alfonso Muriel, Gregory Y H Lip, Samuel Z Goldhaber, Manuel Monreal, RIETE Investigators. Association between preexisting versus newly identified atrial fibrillation and outcomes of patients with acute pulmonary embolism. J Am Heart Assoc. 2021 Sep 7;10(17):e021467. doi: 10.1161/JAHA.121.021467. Epub 2021 Aug 28.

Pulmonary embolism during pregnancy

. Ghazaleh Mehdipoor, David Jiménez , Laurent Bertoletti, Jorge Del Toro, Carmen Fernández-Capitán, Alessandra Bura-Rivière, Cristina Amado, Beatriz Valero, Ángeles Blanco-Molina, Remedios Otero, Egidio Imbalzano, Ramin Khorasani, Martin R Prince, Behnood Bikdeli, Manuel Monreal, RIETE Investigators. Imaging modalities for confirming pulmonary embolism during pregnancy: results from a multicenter international study. Eur Radiol. 2022 Feb;32(2):1238-1246. doi: 10.1007/s00330-021-08161-9. Epub 2021 Jul 30.

Autoimmune disease and venous thromboembolism

. Jaime Borjas Howard, Pablo Ruiz-Sada, Karina de Leeuw, Luciano López-Jiménez, Carme Font, Pablo Javier Marchena, Olga Madridano, Philippe Debourdeau, Karina Meijer, Manuel Monreal, RIETE Investigators. Risk of recurrent venous thromboembolism in patients with autoimmune diseases: data from the Registro Informatizado de Enfermedad TromboEmbólica (RIETE) registry. Br J Haematol. 2021 Jul;194(1):195-199. doi: 10.1111/bjh.17549. Epub 2021 Jun 2.

PE in patients with patent foramen ovale

. K Lacut, E Le Moigne, F Couturaud, C Font, F J Vázquez, I Cañas, J A Díaz-Peromingo, A Gil-Díaz, E Bucherini, M Monreal, RIETE Investigators. Outcomes in patients with acute pulmonary embolism and patent foramen ovale: findings from the RIETE registry. Thromb Res. 2021 Jun;202:59-66. doi: 10.1016/j.thromres.2021.03.005. Epub 2021 Mar 8.

VTE in SOT recipients

. Alberto García-Ortega, Raquel López-Reyes, Gabriel Anguera, Grace Oscullo, Agustina Rivas, Luciano López-Jiménez, Alicia Lorenzo, Isabelle Mahé, Maurizio Ciammaichella, Manuel Monreal, RIETE Investigators. Venous thromboembolism in solid-organ transplant recipients: findings from the RIETE registry. Thromb Res. 2021 May;201:131-138. doi: 10.1016/j.thromres.2021.02.022. Epub 2021 Feb 25.

Impact of obstructive sleep apnea in patients with PE

. Raphael Le Mao, David Jiménez, Behnood Bikdeli, Mateo Porres-Aguilar, Alberto García-Ortega, Vladimir Rosa, Sebastian Schellong, Lucia Mazzolai, Francisco Rivera-Civico, Manuel Monreal, RIETE Investigators. Prognostic impact of obstructive sleep apnea in patients presenting with acute symptomatic pulmonary embolism. Thromb Haemost. 2021 Jun;121(6):808-815. doi: 10.1055/s-0040-1721506. Epub 2020 Dec 30.

Real-world clinical data of VTE during pregnancy and postpartum

. Islam Y Elgendy, Annemarie Fogerty, Ángeles Blanco-Molina, Vladimir Rosa, Sebastian Schellong, Andris Skride, José Portillo, Patricia López-Miguel, Manuel Monreal, Ido Weinberg. Clinical characteristics and outcomes of women presenting with venous thromboembolism during pregnancy and postpartum period: findings from the RIETE Registry. Thromb Haemost. 2020 Oct;120(10):1454-1462. doi: 10.1055/s-0040-1714211.

Psychiatric disorders and PE-related mortality

. Diurbis Velasco, David Jiménez, Behnood Bikdeli, Alfonso Muriel, Pablo Javier Marchena, Inna Tzoran, Radovan Malý, Raquel López-Reyes, Antoni Riera-Mestre, Manuel Monreal, RIETE Investigators. Outcome of patients with acute symptomatic pulmonary embolism and psychiatric disorders. Thromb Res. Sep;193:90-97. doi: 10.1016/j.thromres.2020.05.052.

Role of morbid obesity in patients with venous thromboembolism

. Matteo Giorgi-Pierfranceschi, Juan J López-Núñez, Manuel Monreal, Chiara Cattabiani, Corrado Lodigiani, Pierpaolo di Micco, Behnood Bikdeli, Andrei Braester, Silvia Soler, Francesco Dentali, RIETE researchers. Morbid Obesity and Mortality in Patients With VTE: Findings From Real-Life Clinical Practice. Chest. 2020 Jun;157(6):1617-1625. doi: 10.1016/j.chest.2019.12.040.

Hallux valgus surgery and VTE

. Bavand Bikdeli, Renuka Visvanathan, Ido Weinberg, Agustina Rivas, José Antonio Nieto, Ángel Sampériz, Mónica Loring, Fernando Javier Vázquez, Hugo Hyung Bok Yoo, Behnood Bikdeli, Manuel Monreal. Clinical characteristics and outcomes of venous thromboembolic events after hallux valgus surgery: insights from the RIETE Registry. J Thromb Thrombolysis. 2020 May;49(4):651-658. doi: 10.1007/s11239-019-02025-2.

VTE and autoimmune disorders

. Pablo Ruiz Sada, Juan J López-Núñez, Ángel Sampériz, María José Soto, José María Pedrajas, José Antonio Porras, María Luisa Peris, Alejandro Olivé, Philippe Debourdeau, Federica Pace, Manuel Monreal, RIETE Investigators. Venous Thromboembolism in Patients With Autoimmune Disorders: Findings From the RIETE Registry. Angiology. 2020 Feb;71(2):131-138. doi: 10.1177/0003319719875895.

Acute kidney injury in acute pulmonary embolism

. Martin Murgier, Laurent Bertoletti, Michael Darmon, Fabrice Zeni, Reina Valle, Jorge del Toro, Pilar Llamas, Lucia Mazzolai, Aurora Villalobos, Manuel Monreal, RIETE Investigators. Frequency and prognostic impact of acute kidney injury in patients with acute pulmonary embolism. Data from the RIETE Registry. IntJ Cardiol. 2019 Sep 15;291:121-126. doi: 10.1016/j.ijcard.2019.04.083.

VTE in patients with autoimmune disorders

. Pablo Ruiz Sada, Juan J López-Núñez, Ángel Sampériz, María José Soto, José María Pedrajas, José Antonio Porras, María Luisa Peris, Alejandro Olivé, Philippe Debourdeau, Federica Pace, Manuel Monreal, RIETE Investigators. Venous Thromboembolism in Patients With Autoimmune Disorders: Findings From the RIETE Registry. Angiology. 2020 Feb;71(2):131-138. doi: 10.1177/0003319719875895.

VTE in patients with liver cirrhosis

. Behnood Bikdeli, David Jiménez, Guadalupe Garcia-Tsao, Raquel Barba, Carme Font, María del Carmen Díaz-Pedroche, Lucia Mazzolai, Derek Henry Wallace Little, Antonella Tufano, Alfonso J Tafur, Deborah Siegal, Gregory Y H Lip, Manuel Monreal, RIETE Investigators. Venous Thromboembolism in Patients with Liver Cirrhosis: Findings from the RIETE (Registro Informatizado de la Enfermedad TromboEmbolica) Registry. Semin Thromb Hemost. 2019 Nov;45(8):793-801. doi: 10.1055/s-0039-1697682.

First published series on a subgroup of patients at increased risk for bleeding: Fragile patients with VTE

. Moustafa F, Giorgi Pierfranceschi M, Di Micco P, Bucherini E, Lorenzo A, Villalobos A, Nieto JA, Valero B, Sampériz ÁL, Monreal M; RIETE Investigators. Clinical outcomes during anticoagulant therapy in fragile patients with venous thromboembolism. Res Pract Thromb Haemost. 2017 Sep 4;1(2):172-179. doi: 10.1002/rth2.12036. eCollection 2017 Oct.

VTE in neurosurgical patients

. Cote L, Greenberg S, Caprini J, Arcelus J, López-Jiménez L, Rosa V, Schellong S, Monreal M and the RIETE Investigators. Outcomes in Neurosurgical Patients Who Develop Venous Thromboembolism (VTE): A Review of the RIETE Registry. Clin Appl Thromb Hemost 2014 Nov; 20(8): 772-8.

Cava filter in patients at risk for bleeding

. Muriel A, Jiménez D, Aujesky D, Bertoletti L, Decousus H, Laporte S, Mismetti P, Muñoz FJ, Yusen R, Monreal M and the RIETE Investigators. Survival effects of inferior vena cava filter in patients with acute symptomatic venous thromboembolism and a significant bleeding risk. J Am Coll Cardiol 2014 April; 63(16): 1675-83.

LMWH or UFH in renal failure

. Trujillo-Santos J, Schellong S, Falgá C, Zorrilla V, Gallego P, Barrón M, Monreal M and the RIETE investigators. Low-molecular-weight or unfractionated heparin in venous thromboembolism: The influence of renal function. Am J Med 2013 May; 126(5): 425-434.

VTE in patients with dementia

. Núñez MJ, Villalba JC, Cebrián E, Visoná A, López-Jiménez L, Núñez M, Szwebel TA, Luque JM, Jaras MJ, Monreal M for the RIETE investigators. Venous thromboembolism in immobilized patients with dementia. Findings from the RIETE Registry. Thromb Res 2012 Aug; 130(2): 173-7.

VTE in patients with recent cerebral bleeding

. Lobo JL, Nieto JA, Zorrilla V, Garrido N, Madridano O; Ruíz J, Farge-Bancel D, Tiberio G, Uresandi F, Monreal M, and the RIETE Investigators. Venous thromboembolism in patients with intracranial haemorrhage. Thromb Haemost 2011 Oct; 106(4): 750-752.

VTE in patients older than 90 years

. Vasco B, Villalba JC, López-Jiménez L, Falgá C, Montes J, Trujillo-Santos J, Monreal M, for the RIETE Investigators. Venous thromboembolism in nonagenarians. Findings from the RIETE Registry. Thromb Haemost 2009 Jun; 101(6): 1112-8.

Long-term treatment of VTE in renal failure

. Falgá C, Capdevila JA, Soler S, Rabuñal R, Sánchez Muñoz-Torrero JF, Gallego P, Monreal M for the RIETE Investigators. Clinical outcome of patients with venous thromboembolism and renal insufficiency. Findings from the RIETE Registry. Thromb Haemost 2007 Oct; 98(4): 771-6.

Suboptimal doses of LMWH

. Bruscas MJ, Nieto JA, Pérez-Pinar M, López Jiménez L, Fernández-Capitán C, López Chuliá F, Orué-Lecue MT for the RIETE Investigators. Suboptimal doses of low molecular weight heparin and acute venous thromboembolism. Data from the RIETE Registry. Ann Hematol 2007Jul; 86(7): 519-26.

VTE in renal insufficiency

. Monreal M, Falgá C, Valle R, Barba R, Bosco J, Beato JL, Maestre A and the RIETE investigators. Venous thromboembolism in patients with renal insufficiency: findings from the RIETE Registry. Am J Med 2006 Dec; 119 (12): 1073-9.

VTE after major bleeding

. Nieto JA, Bruscas MJ, Ruiz-Ribo D, Trujillo- Santos J, Valle R, Ruiz-Giménez N, Monreal M for the RIETE Investigators. Acute venous thromboembolism in patients with recent major bleeding. The influence of the site of bleeding and the time elapsed on outcome. J Thromb Haemost 2006 Nov; 4(11): 2367-72.

VTE in patients with chronic lung disease or heart failure

. Monreal M, Sánchez Muñoz JF, Naraine VS, Jiménez D, Soler S, Rabuñal R, Gallego P for the RIETE investigators. Pulmonary embolism in patients with chronic obstructive pulmonary disease or congestive heart failure. Am J Med 2006 Oct; 119(10): 851-8.

VTE in elderly

. López-Jiménez L, Montero M, González-Fajardo JA, Arcelus JI, Suárez C, Lobo JL, Monreal M and the RIETE Investigators. Venous thromboembolism in very elderly patients: findings from a prospective Registry (RIETE). Haematologica 2006 Aug; 91(8): 1046-51.