Deep vein thrombosis

Predicting long-term complications after deep vein thrombosis

. Pedro Parra-Caballero, Jean-Philippe Galanaud, Paolo Prandoni, Yaser Jenab, Pablo Demelo-Rodríguez, Sonia Otálora, Giorgina Gabriela Salgueiro Origlia, Aída Gil-Díaz, José María Pedrajas, Manuel Monreal; RIETE Investigators. Distinct predictors of post-thrombotic symptoms, signs, and ulcers after a first episode deep vein thrombosis: a RIETE Registry study. Eur J Vasc Endovasc Surg. 2026 Jun 8:S1078-5884(26)00567-8. doi: 10.1016/j.ejvs.2026.06.006.

 

Real-world evidence for DOACs in upper extremity deep vein thrombosis

. Pedro Ruiz-Artacho, Ramón Lecumberri, Javier Trujillo-Santos, Fahd Beddar Chaib, Farès Moustafa, Alicia Lorenzo, Covadonga Gómez-Cuervo, Marijan Bosevski, Manuel Monreal; RIETE Investigators. Direct oral anticoagulants versus standard therapy in upper extremity deep vein thrombosis: real-world evidence.. Thromb Haemost. 2026 Mar;126(3):287-296. doi: 10.1055/a-2615-4513. Epub 2025 May 19.

 

Statins for isolated DVT

. Carmine Siniscalchi, Behnood Bikdeli, David Jiménez, José María Suriñach, Pablo Demelo-Rodríguez, Farès Moustafa, Aída Gil-Díaz, Alberto García-Ortega, Hanh My Bui, Manuel Monreal, RIETE Investigators. Statin use and mortality in patients with deep vein thrombosis. Data from the RIETE Registry. Thromb Res. 2024 Apr:236:88-96. doi: 10.1016/j.thromres.2024.02.024. Epub 2024 Feb 24.

 

Lower-limb deep vein thrombosis symptoms and mortality for EP

. Álvaro Dubois-Silva, Cristina Barbagelata-López, Patricia Piñeiro-Parga, Luciano López-Jiménez, Antoni Riera-Mestre, Sebastian Schellong, Judith Catella, Marijan Bosevski, Mireia Roca Toledo, Manuel Monreal, RIETE Investigators. Deep vein thrombosis symptoms and 30-day mortality in acute pulmonary embolism. Eur J Intern Med. 2023 Feb:108:43-51. doi: 10.1016/j.ejim.2022.11.007. Epub 2022 Nov 16.

 

Outcomes of patients with isolated distal deep vein thrombosis

. Behnood Bikdeli, César Caraballo, Javier Trujillo-Santos, Jean Philippe Galanaud, Pierpaolo di Micco, Vladimir Rosa, Gemma Vidal Cusidó, Sebastian Schellong, Meritxell Mellado, María del Valle Morales, Olga Gavín-Sebastián, Lucia Mazzolai, Harlan M Krumholz, Manuel Monreal, RIETE Investigators. Clinical presentation and short- and long-term outcomes in patients with isolated distal deep vein thrombosis vs proximal deep vein thrombosis in the RIETE Registry. JAMA Cardiol. 2022 Aug 1;7(8):857-865. doi: 10.1001/jamacardio.2022.1988.

 

DVT and thoracic outlet syndrome

. Vladimir Rosa, Cassius Iyad Ochoa Chaar, Olivier Espitia, Sonia Otalora, Luciano López-Jiménez, Pablo Ruiz-Sada, Peter Verhamme, Juan Francisco Sánchez Muñoz-Torrero, Pablo Javier Marchena, Manuel Monreal, RIETE Investigators. A RIETE registry analysis of patients with upper extremity deep vein thrombosis and thoracic outlet syndrome. Thromb Res. 2022 May;213:65-70. doi: 10.1016/j.thromres.2021.12.030. Epub 2022 Jan 4

 

Patient characteristics according to the bleeding site

. Behnood Bikdeli, Farès Moustafa, José Antonio Nieto, Alfred I Lee, Nuria Ruíz-Giménez, Alicia Lorenzo, Sebastian Schellong, Silvia Soler, Salvador Ortiz, Mª del Valle Morales , Marijan Bosevski, Olga Gavín, Gregory Y H Lip, Manuel Monreal, RIETE Investigators. Clinical characteristics, time course, and outcomes of major bleeding according to bleeding site in patients with venous thromboembolism. Thromb Res. 2022 Mar;211:10-18. doi: 10.1016/j.thromres.2022.01.007. Epub 2022 Jan 14.

 

Ultrasound finding of residual thrombosis

. M Bosevski, G Krstevski, P Di Micco, A Fidalgo, M Loring, J A Porras, M Mellado, J F Sánchez Muñoz-Torrero, J R Vela, I Tzoran, M Monreal, RIETE Investigators. Risk for post-thrombotic syndrome after lower-limb deep vein thrombosis: location of the thrombus or residual thrombi?. Angiol Sosud Khir. 2021;27(2):62-72. doi: 10.33529/ANGIO2021108.

 

Concomitant superficial vein thrombosis (SVT) in patients with lower-limb DVT

. Álvaro Dubois-Silva, Cristina Barbagelata-López, Patricia Piñeiro-Parga, Iria Francisco, Conxita Falgà, Raimundo Tirado, José María Suriñach, Jerónimo Ramón Vela, Carmen Mella, Isabelle Quere, Carmine Siniscalchi, Manuel Monreal, RIETE Investigators. Prognostic significance of concomitant superficial vein thrombosis in patients with deep vein thrombosis of the lower limbs. Thromb Haemost. 2021 Dec;121(12):1650-1659. doi: 10.1055/a-1414-5055. Epub 2021 Apr 30.

 

Isolated distal deep-vein thrombosis and DOACs

. Jean-Philippe Galanaud, Javier Trujillo-Santos, Behnood Bikdeli, Pierpaolo Di Micco, Cristiano Bortoluzzi, Laurent Bertoletti, José María Pedrajas, Aitor Ballaz, Joaquín Alfonso, Manuel Monreal, RIETE Investigators. Management of isolated distal deep-vein thrombosis with direct oral anticoagulants in the RIETE registry. J Thromb Thrombolysis. 2021 Aug;52(2):532-541. doi: 10.1007/s11239-020-02347-6. Epub 2020 Nov 28.

 

Inferior vena cava agenesis and deep venous thrombosis

. Antonella Tufano, Luciano López-Jiménez , Behnood Bikdeli, Fernando García-Bragado, Lucia Mazzolai , Maria Amitrano, Covadonga Gómez-Cuervo, Pablo Javier Marchena, Olga Madridano, Manuel Monreal, Pierpaolo Di Micco, RIETE Investigators. Inferior vena cava agenesis in patients with lower limb deep vein thrombosis in the RIETE Registry. When and why to suspect. Int J Cardio. 2020 Apr 15;305:115-119. doi: 10.1016/j.ijcard.2020.01.013. Epub 2020 Jan 15.

 

Venous thromboembolism in young adults?

. Beatriz Lacruz , Gregorio Tiberio, Ana Latorre, Joan Carles Villalba, Behnood Bikdeli, Jana Hirmerova, Alicia Lorenzo, Meritxell Mellado, Inmaculada Cañas, Manuel Monreal, RIETE Investigators. Venous thromboembolism in young adults: findings from the RIETE Registry. Eur J Intern Med. 2019 May;63:27-33. doi: 10.1016/j.ejim.2019.02.007. Epub 2019 Mar 11.

 

Predictors of post-thrombotic ulcer after acute DVT

. Galanaud JP, Bertoletti L, Amitrano M, Fernández-Capitán C, Pedrajas JM, Rosa V, Barrón M, Lorenzo A, Madridano O, Quéré I, Kahn SR, Prandoni P, Monreal M; RIETE registry investigators. Predictors of Post-Thrombotic Ulcer after Acute DVT: The RIETE Registry. Thromb Haemost. 2018 Feb;118(2):320-328. doi: 10.1160/TH17-08-0598. Epub 2018 Jan 29.

 

Impact of thrombus sidedness

. Bikdeli B, Sharif-Kashani B, Bikdeli B, Valle R, Falga C, Riera-Mestre A, Mazzolai L, Verhamme P, Wells PS, Torrero JFSM, Lopez-Jiménez L, Monreal M; RIETE Investigators. Impact of Thrombus Sidedness on Presentation and Outcomes of Patients with Proximal Lower Extremity Deep Vein Thrombosis. Semin Thromb Hemost. 2018 Jan 12. doi: 10.1055/s-0037-1621716.

 

Venous thromboembolism and thrombophilia: gender differences

. Tzoran I, Papadakis E, Brenner B, Valle R, López-Jiménez L, García-Bragado F, Riera-Mestre A, Villalobos A, Quintavalla R, Monreal M; RIETE Investigators. Gender-related differences in the outcome of patients with venous thromboembolism and thrombophilia. Thromb Res. 2017 Mar;151 Suppl 1:S11-S15. doi: 10.1016/S0049-3848(17)30060-9.

 

Noncatheter-associated upper extremity deep venous thrombosis

. Newton DH, Monreal Bosch M, Amendola M, Wolfe L, Perez Ductor C, Lecumberri R, Levy MM; RIETE Investigators. Analysis of noncatheter-associated upper extremity deep venous thrombosis from the RIETE registry. J Vasc Surg Venous Lymphat Disord. 2017 Jan;5(1):18-24.e1. doi: 10.1016/j.jvsv.2016.08.002. Epub 2016 Oct 27.

 

Upper and lower limb deep vein thrombosis

. Cote LP, Greenberg S, Caprini JA, Tafur A, Choi C, Muñoz FJ, Skride A, Valero B, Porras JA, Ciammaichella M, Hernández-Blasco LM, Monreal M; RIETE Investigators. Comparisons Between Upper and Lower Extremity Deep Vein Thrombosis: A Review of the RIETE Registry. Clin Appl Thromb Hemost. 2017 Oct;23(7):748-754. doi: 10.1177/1076029616663847. Epub 2016 Aug 29.

 

Venous thromboembolism in centenarians

. Lacruz B, Tiberio G, Núñez MJ, López-Jiménez L, Riera-Mestre A, Tiraferri E, Verhamme P, Mazzolai L, González J, Monreal M; RIETE Investigators. Venous thromboembolism in centenarians: Findings from the RIETE registry.Eur J Intern Med. 2016 Dec;36:62-66. doi: 10.1016/j.ejim.2016.07.025. Epub 2016 Aug 3.

 

Trends and outcomes in DVT management (2001-2014)

. Morillo R, Jiménez D, Aibar MÁ, Mastroiacovo D, Wells PS, Sampériz Á, Saraiva de Sousa M, Muriel A, Yusen RD, Monreal M; RIETE investigators. DVT Management and Outcome Trends, 2001 to 2014. Chest. 2016 Aug;150(2):374-83. doi: 10.1016/j.chest.2016.03.046. Epub 2016 Apr 9.

 

Arterial ischemic events in VTE patients receiving anticoagulant therapy

. Madridano O, del Toro J, Lorenzo A, Martín M, Gómez Cerezo J, Hernández L, Prandoni P, Monreal M; RIETE Investigators. Subsequent arterial ischemic events in patients receiving anticoagulant therapy for venous thromboembolism. J Vasc Surg Venous Lymphat Disord. 2015 Apr;3(2):135-41.e1. doi: 10.1016/j.jvsv.2014.11.002. Epub 2015 Mar 13.

 

Thromboprophylaxis in patients after an acute medical illness

. Merah A, Bertoletti L, Ginzarly M, Zeltser D, Barrón M, Cañas I, Villalta J, Bucherini E, Monreal M; RIETE investigators. Prior thromboprophylaxis and outcome in patients experiencing acute venous thromboembolism after an acute medical illness. Eur J Intern Med. 2016 May;30:72-76. doi: 10.1016/j.ejim.2016.02.022. Epub 2016 Mar 11.

 

Recurrences in patients with recent gestational VTE

. Barillari G, Londero AP, Brenner B, Nauffal D, Muñoz-Torrero JF, Del Molino F, Moustafa F, Madridano O, Martín-Martos F, Monreal M; RIETE Investigators. Recurrence of venous thromboembolism in patients with recent gestational deep vein thrombosis or pulmonary embolism: Findings from the RIETE Registry. Eur J Intern Med. 2016 Jul;32:53-9. doi: 10.1016/j.ejim.2016.02.013. Epub 2016 Mar 10.

 

Catheter-associated DVT

. Baumann Kreuziger L, Cote L, Verhamme P, Greenberg S, Caprini J, Muñoz FJ, Valle R, Monreal Bosch M; RIETE Investigators. A RIETE registry analysis of recurrent thromboembolism and hemorrhage in patients with catheter-related thrombosis. J Vasc Surg Venous Lymphat Disord. 2015 Jul;3(3):243-250.e1

 

Prognostic score in arm DVT

. Rosa-Salazar V, Trujillo-Santos J, Díaz Peromingo JA, Apollonio A, Sanz O, Malý R, Muñoz-Rodriguez FJ, Serrano JC, Soler S, Monreal M and the RIETE Investigators. A prognostic score to identify low-risk outpatients with acute deep vein thrombosis in the upper extremity. J Thromb Haemost 2015 Jul; 13(7): 1274-8.

 

Scale to identify patients with low risk DVT

. Trujillo-Santos J, Lozano F, Lorente MA, Adarraga MD, Hirmerova J, Del Toro J, Mazzolai L, Barillari G, Barrón M, Monreal M and the RIETE Investigators. A prognostic score to identify low-risk outpatients with acute deep vein thrombosis in the lower limbs. Am J Med 2015 Jan; 128(1): 90.e9-15.

 

DVT treatment at home or in hospital

. Lozano F, Trujillo-Santos J, Barrón M, Gallego P, Babalis D, Santos M, Falgá C, Monreal M for the RIETE Investigators. Home versus in-hospital treatment of outpatients with acute deep venous thrombosis of the lower limbs. J Vasc Surg 2014 May; 59(5): 1362-67e1.

 

Prognostic score in DVT patients

. Tzoran I, Saharov G, Brenner B, Delsart D, Román P, Visoná A, Jiménez D, Monreal M and the RIETE investigators. Silent pulmonary embolism in patients with proximal deep vein thrombosis in the lower limbs. J Thromb Haemost 2012 Apr; 10(4): 564-71.

 

DVT in the elderly

. Sánchez Muñoz-Torrero JF, Bounameaux H, Pedrajas JM, Lorenzo A, Rubio S, Kearon C, Hernández L, Monreal M, and the RIETE Investigators. Effects of age on the risk of dying from pulmonary embolism or bleeding during treatment of deep-vein thrombosis. J Vasc Surg 2011 Dec; 54(6 Suppl):26S-32S.

 

Distal DVT in the legs

. Galanaud JP, Quenet S, Rivron-Guillot K, Quere I, Sánchez Muñoz-Torrero JF, Tolosa C, Monreal M and the RIETE Investigators.Comparison of the clinical history of symptomatic isolated distal deep-vein thrombosis vs. proximal deep-vein thrombosis in 11.086 patients. J Thromb Haemost 2009 Dec; 7(12): 2028-34.

 

DVT in the arm

. Muñoz FJ, Mismetti P, Poggio R, Valle R, Barrón M, Guil M, Monreal M for the RIETE Investigators. Clinical outcome of patients with upper-extremity deep vein thrombosis. Results from the RIETE Registry. Chest 2008 Jan; 133 (1): 143-8.

 

Outcome after DVT

. Trujillo-Santos J, Herrera S, Page MA, Soto MJ, Raventos A, Sánchez R, Monreal M and the RIETE investigators. Predicting adverse outcome in outpatients with acute deep vein thrombosis. Finding from the RIETE Registry. J Vasc Surg 2006 Oct; 44(4): 789-93.

 

DVT and PE are the same disease?

. Monreal M, Barba R, Tolosa C, Tiberio G, Todolí JA, Samperiz AL and the RIETE Investigators. Deep vein thrombosis and pulmonary embolism. The same disease? Pathophysiol Haemost Thromb 2006; 35 (1-2): 133-5.